Hyaluronic Acid Injection
Harnessing the Power of Hyaluronic Acid injection in non-surgical knee treatments.
Treatment Overview
Hyaluronic Acid Injection for Knee Osteoarthritis:
Knee osteoarthritis (OA) is a degenerative joint disease characterized by the breakdown of cartilage, leading to pain, stiffness, and reduced mobility. Hyaluronic acid (HA) injections, also known as viscosupplementation, are a popular non-surgical treatment option for managing knee OA. This article explores the types of HA injections, their molecular weight, function, and their role in treating knee osteoarthritis.








What is Hyaluronic Acid?
Hyaluronic acid is a naturally occurring substance found in the synovial fluid of joints. It acts as a lubricant and shock absorber, enabling smooth and pain-free joint movement. In knee osteoarthritis, the concentration and quality of HA in the synovial fluid decrease, contributing to joint pain and stiffness.
Types of Hyaluronic Acid Injections
HA injections come in various forms, categorized primarily by their molecular weight:
- Characteristics:
- Smaller HA molecules
- Typically requires multiple injections (3-5) over several weeks
- Function:
- Provides short-term pain relief and improves joint lubrication
- Examples:
- Hyalgan, Hyal injection.
- Characteristics:
- Larger HA molecules
- Often administered as a single injection or a series of 1-3 injections
- Function:
- May provide longer-lasting relief and improve joint function
- Examples:
- Synvisc, Atri-Plus.
- Characteristics:
- Chemically modified to form cross-links between HA molecules
- Enhances the viscosity and durability of the injection
- Function:
- Provides prolonged pain relief and improved joint mechanics
- Examples:
- Durolane, Synvisc.
Hyaluronic Acid injection in knee treatments

How it works
Function of Hyaluronic Acid in Knee Osteoarthritis
HA injections aim to restore the natural viscoelastic properties of the synovial fluid in the knee joint. The primary functions of HA in treating knee osteoarthritis include:
Reduces friction between the articular surfaces, facilitating smoother joint movements.
Distributes mechanical loads more evenly across the joint, reducing stress on the cartilage.
Alleviates pain by enhancing joint lubrication and reducing inflammation.
Enhances overall joint function, leading to better mobility and quality of life.
Benefits
Role of Hyaluronic Acid in Treating Knee Osteoarthritis
HA injections play a significant role in the non-surgical management of knee osteoarthritis:
Provides effective pain relief and reduces stiffness in the knee joint.
Helps patients regain better joint function and mobility, allowing them to perform daily activities with less discomfort.
May delay the need for more invasive treatments like total knee replacement, especially in early to moderate stages of OA.
Generally well-tolerated with a low risk of adverse effects, making it a suitable option for many patients.

Conclusion
Hyaluronic acid injections offer a promising non-surgical treatment option for knee osteoarthritis. By restoring the natural lubrication and shock-absorbing properties of the synovial fluid, HA injections can significantly relieve pain, improve joint function, and enhance the quality of life for individuals with knee OA. At EA Clinic, we specialize in advanced non-surgical treatments for knee pain, including hyaluronic acid injections, to help you stay active and pain-free.